{"id":112984,"date":"2026-01-22T00:00:46","date_gmt":"2026-01-21T19:00:46","guid":{"rendered":"https:\/\/thedermreview.com\/?p=112984"},"modified":"2026-03-25T15:15:24","modified_gmt":"2026-03-25T10:15:24","slug":"skinmedica-tns-advanced-serum-review","status":"publish","type":"post","link":"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/","title":{"rendered":"SkinMedica TNA Serum Review"},"content":{"rendered":"<p dir=\"ltr\"><strong><span style=\"font-size: 14pt;\">TOP SKINCARE PICKS<\/span><\/strong><\/p>\n<p dir=\"ltr\">\n<table id=\"tablepress-334\" class=\"tablepress tablepress-id-334 tablepress-responsive\">\n<thead>\n<tr class=\"row-1 odd\">\n\t<th class=\"column-1\"><\/th><th class=\"column-2\">Rank<\/th><th class=\"column-3\">Brand<\/th><th class=\"column-4\"><\/th><th class=\"column-5\"><\/th><th class=\"column-6\"><\/th><th class=\"column-7\"><\/th><th class=\"column-8\">Link<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-hover\">\n<tr class=\"row-2 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  1<\/td><td class=\"column-3\">Carrot &amp; Stick <\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"http:\/\/thedermreview.com\/carrot-and-stick-review\/\" rel=\u201dnofollow\u201d>Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-3 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  2<\/td><td class=\"column-3\">Formulyst<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/formulyst-review\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-4 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  3<\/td><td class=\"column-3\">Skinceuticals<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/skinceuticals-reviews\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-5 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">-<\/td><td class=\"column-3\">SkinMedica TNS Advanced Serum<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-334 from cache --><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Did you know SkinMedica is the brand that created the first topical growth factors solution back in 2001? Known as the \u201cTNS Recovery Complex\u201d, the launch of this blend of growth factors pioneered the creation of the entire category.\u00a0<\/span><span style=\"font-weight: 400;\">Then, in 2008, the brand launched their TNS Essential Serum, which remained their most advanced product \u2014 until TNS Advanced Serum was released.\u00a0<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">While these serums have similar names, TNS Advanced Serum is actually a completely different serum compared with TNS Essential Serum. In fact, the only similarity is that they both contain the patented growth factors.\u00a0<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\"><strong>Before splurging on this pricey serum<\/strong> (did we mention it\u2019s $295 for just one ounce?), keep scrolling to read our SkinMedica TNS Advanced Serum review. <span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;A common question about this brand is if the products are worth the cost. _ products are expensive, for example, the _ is _. \\n\\nIn our opinion, _ products aren\u2019t worth the money, simply because there are other skincare brands that offer similar products that are less expensive. \\n\\nOne brand is Carrot &amp; Stick, a clean skincare brand that perfectly balances the gentle nurturing of plants with the powerful results of innovative science.\\n\\nCarrot &amp; Stick intro bundles deliver great value for money because you can bundle 3 full size products worth up to $240 for $88. \\n&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:1049345,&quot;3&quot;:{&quot;1&quot;:0},&quot;11&quot;:4,&quot;12&quot;:0,&quot;23&quot;:1}\" data-sheets-textstyleruns=\"{&quot;1&quot;:0}\uee10{&quot;1&quot;:293,&quot;2&quot;:{&quot;2&quot;:{&quot;1&quot;:2,&quot;2&quot;:1136076},&quot;9&quot;:1}}\uee10{&quot;1&quot;:308}\uee10{&quot;1&quot;:552,&quot;2&quot;:{&quot;7&quot;:1}}\uee10{&quot;1&quot;:556}\" data-sheets-hyperlinkruns=\"{&quot;1&quot;:293,&quot;2&quot;:&quot;https:\/\/carrotstick.com\/collections\/best-sellers\/&quot;}\uee10{&quot;1&quot;:308}\">In our opinion, SkinMedia Skincare products aren\u2019t worth the money, simply because there are other skincare brands that offer similar products that are less expensive\u00a0<\/span><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;A common question about this brand is if the products are worth the cost. _ products are expensive, for example, the _ is _. \\n\\nIn our opinion, _ products aren\u2019t worth the money, simply because there are other skincare brands that offer similar products that are less expensive. \\n\\nOne brand is Carrot &amp; Stick, a clean skincare brand that perfectly balances the gentle nurturing of plants with the powerful results of innovative science.\\n\\nCarrot &amp; Stick intro bundles deliver great value for money because you can bundle 3 full size products worth up to $240 for $88. \\n&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:1049345,&quot;3&quot;:{&quot;1&quot;:0},&quot;11&quot;:4,&quot;12&quot;:0,&quot;23&quot;:1}\" data-sheets-textstyleruns=\"{&quot;1&quot;:0}\uee10{&quot;1&quot;:293,&quot;2&quot;:{&quot;2&quot;:{&quot;1&quot;:2,&quot;2&quot;:1136076},&quot;9&quot;:1}}\uee10{&quot;1&quot;:308}\uee10{&quot;1&quot;:552,&quot;2&quot;:{&quot;7&quot;:1}}\uee10{&quot;1&quot;:556}\" data-sheets-hyperlinkruns=\"{&quot;1&quot;:293,&quot;2&quot;:&quot;https:\/\/carrotstick.com\/collections\/best-sellers\/&quot;}\uee10{&quot;1&quot;:308}\">One brand is\u00a0<a class=\"in-cell-link\" target=\"_blank\" href=\"https:\/\/carrotstick.com\/collections\/best-sellers\/\" rel=\"nofollow noopener\"><strong>Carrot &amp; Stick,<\/strong><\/a>\u00a0a clean skincare brand that perfectly balances the gentle nurturing of plants with the powerful results of innovative science.<\/span><\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">We\u2019ll give you all the details on the key ingredients in this formula, as well as the research that supports (or doesn\u2019t support) their use in skin care.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">We\u2019ll also share some SkinMedica TNS Advanced Serum reviews so that you can get an idea of what customers really think of this product.<\/span><\/p>\n<p dir=\"ltr\"><span data-sheets-value=\"{&quot;1&quot;:2,&quot;2&quot;:&quot;OUR TOP SKINCARE PICKS\\n\\n\n&lt;table id=&quot;tablepress-190&quot; class=&quot;tablepress tablepress-id-190 tablepress-responsive&quot;&gt;\n&lt;thead&gt;\n&lt;tr class=&quot;row-1 odd&quot;&gt;\n\t&lt;th class=&quot;column-1&quot;&gt;&lt;\/th&gt;&lt;th class=&quot;column-2&quot;&gt;Rank&lt;\/th&gt;&lt;th class=&quot;column-3&quot;&gt;Brand&lt;\/th&gt;&lt;th class=&quot;column-4&quot;&gt;&lt;\/th&gt;&lt;th class=&quot;column-5&quot;&gt;&lt;\/th&gt;&lt;th class=&quot;column-6&quot;&gt;&lt;\/th&gt;&lt;th class=&quot;column-7&quot;&gt;&lt;\/th&gt;&lt;th class=&quot;column-8&quot;&gt;Link&lt;\/th&gt;\n&lt;\/tr&gt;\n&lt;\/thead&gt;\n&lt;tbody class=&quot;row-hover&quot;&gt;\n&lt;tr class=&quot;row-2 even&quot;&gt;\n\t&lt;td class=&quot;column-1&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-2&quot;&gt;  1&lt;\/td&gt;&lt;td class=&quot;column-3&quot;&gt;Carrot &amp; Stick &lt;\/td&gt;&lt;td class=&quot;column-4&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-5&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-6&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-7&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-8&quot;&gt;&lt;a href=&quot;http:\/\/thedermreview.com\/carrot-and-stick-review\/&quot; rel=\u201dnofollow\u201d&gt;Review&lt;\/a&gt;&lt;\/td&gt;\n&lt;\/tr&gt;\n&lt;tr class=&quot;row-3 odd&quot;&gt;\n\t&lt;td class=&quot;column-1&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-2&quot;&gt;  2&lt;\/td&gt;&lt;td class=&quot;column-3&quot;&gt;Formulyst&lt;\/td&gt;&lt;td class=&quot;column-4&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-5&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-6&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-7&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-8&quot;&gt;&lt;a href=&quot;https:\/\/thedermreview.com\/formulyst-review\/&quot;&gt;Review&lt;\/a&gt;&lt;\/td&gt;\n&lt;\/tr&gt;\n&lt;tr class=&quot;row-4 even&quot;&gt;\n\t&lt;td class=&quot;column-1&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-2&quot;&gt;  3&lt;\/td&gt;&lt;td class=&quot;column-3&quot;&gt;Skinceuticals&lt;\/td&gt;&lt;td class=&quot;column-4&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-5&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-6&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-7&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-8&quot;&gt;&lt;a href=&quot;https:\/\/thedermreview.com\/skinceuticals-reviews\/&quot;&gt;Review&lt;\/a&gt;&lt;\/td&gt;\n&lt;\/tr&gt;\n&lt;tr class=&quot;row-5 odd&quot;&gt;\n\t&lt;td class=&quot;column-1&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-2&quot;&gt;-&lt;\/td&gt;&lt;td class=&quot;column-3&quot;&gt;Skinmedica TNS Advanced Serum&lt;\/td&gt;&lt;td class=&quot;column-4&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-5&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-6&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-7&quot;&gt;&lt;\/td&gt;&lt;td class=&quot;column-8&quot;&gt;&lt;\/td&gt;\n&lt;\/tr&gt;\n&lt;\/tbody&gt;\n&lt;\/table&gt;\n&lt;!-- #tablepress-190 from cache --&gt;&quot;}\" data-sheets-userformat=\"{&quot;2&quot;:513,&quot;3&quot;:{&quot;1&quot;:0},&quot;12&quot;:0}\" data-sheets-formula=\"=CONCATENATE(&quot;OUR TOP SKINCARE PICKS &quot;,R[0]C[-1])\"><strong>OUR TOP SKINCARE PICKS<\/strong><\/span><\/p>\n\n<table id=\"tablepress-190-no-2\" class=\"tablepress tablepress-id-190 tablepress-responsive\">\n<thead>\n<tr class=\"row-1 odd\">\n\t<th class=\"column-1\"><\/th><th class=\"column-2\">Rank<\/th><th class=\"column-3\">Brand<\/th><th class=\"column-4\"><\/th><th class=\"column-5\"><\/th><th class=\"column-6\"><\/th><th class=\"column-7\"><\/th><th class=\"column-8\">Link<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-hover\">\n<tr class=\"row-2 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  1<\/td><td class=\"column-3\">Carrot &amp; Stick <\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"http:\/\/thedermreview.com\/carrot-and-stick-review\/\" rel=\u201dnofollow\u201d>Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-3 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  2<\/td><td class=\"column-3\">Formulyst<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/formulyst-review\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-4 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  3<\/td><td class=\"column-3\">Skinceuticals<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/skinceuticals-reviews\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-5 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">-<\/td><td class=\"column-3\">Skinmedica TNS Advanced Serum<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-190-no-2 from cache -->\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">Is SkinMedica TNS Advanced Serum Right For You?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Before we get into the details, here\u2019s the TL;DR if you just want to know whether or not\u00a0 SkinMedica TNS Advanced Serum is right for you.<\/span><\/p>\n<ul>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Key ingredients? <\/b><span style=\"font-weight: 400;\">Growth Factors, Peptides, Botanical and Marine Extracts<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Skin type?<\/b><span style=\"font-weight: 400;\"> All skin types; ideal for mature skin<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Texture? <\/b><span style=\"font-weight: 400;\">Lightweight serum<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Fragrance?<\/b><span style=\"font-weight: 400;\"> No<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Cruelty free? <\/b><span style=\"font-weight: 400;\">Unknown<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"2\"><b>Cost? <\/b><span style=\"font-weight: 400;\">$295 USD for 1 fl oz.<\/span><\/li>\n<\/ul>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">What Are The Key Ingredients in SkinMedica TNS Advanced Serum?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">SkinMedica TNS Advanced Serum is said to improve the appearance of coarse wrinkles, fine lines, skin tone, and texture while also addressing sagging skin. According to the brand, you can see visible results in just 2 weeks and results continue to improve through 24 weeks of use.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">The serum actually consists of two formulations that are dispensed via a dual chamber system; chamber 1 includes TNS-MR and chamber 2 consists of Renessensce (RSC) Advanced. Read on to learn exactly what\u2019s in each of these formulations and how the ingredients will affect your skin.\u00a0<\/span><\/p>\n<p dir=\"ltr\"><b>TNS-MR<\/b><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">TNS-MR includes human fibroblast conditioned media, the blend of patented growth factors that gave SkinMedica its reputation.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Growth factors are messenger proteins that are inherent in our bodies and are capable of stimulating cellular growth, proliferation, healing, and cellular differentiation. Growth factors play an important role in maintaining healthy skin, and topical application may help improve the appearance of fine lines, wrinkles, skin tone and texture.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Furthermore, TNS-MR contains two peptides: Progeline (Trifluoroacetyl Tripeptide-2) and Prolixir S20 (Dimer Tripeptide-43).<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Progeline works by helping your skin to repair itself and therefore prevent signs of aging. You see, damaged skin cells need to constantly repair themselves in order for your skin to appear smooth and supple. Research <\/span><span style=\"font-weight: 400;\">has shown that a protein called progerin interrupts important tissue repair processes, which can lead to visible signs of skin aging. That\u2019s why progerin is called the \u201cskin-aging protein\u201d. <\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">The proprietary ingredient Progeline has been developed to inhibit the synthesis of progerin by up to 22 percent.\u00a0<\/span><span style=\"font-weight: 400;\"><\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Prolixir S20 is a patent-pending dimer tripeptide specifically designed to target the Ubiquitin-Proteasome (Ub-P) System and to help achieve successful aging through a sustained proteasome efficacy and less protein damage.<\/span><\/p>\n<p dir=\"ltr\"><strong>Peptides are designed to\u00a0support amino acids, which are the building blocks for <em>collagen\u00a0<\/em>production.\u00a0We recommend taking a look at the\u00a0<a href=\"https:\/\/www.carrotstick.com\/product\/the-repair-serum\/\" target=\"_blank\" rel=\"noopener nofollow\">Carrot &amp; Stick The Repair Serum.<\/a> It contains 7 peptides for smoother, firmer looking skin.<\/strong><\/p>\n<p dir=\"ltr\"><b>Renessensce (RSC) Advanced\u00a0<\/b><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">The second chamber of SkinMedica TNS Advanced Serum contains Renessensce (RSC) Advanced, which is designed to support the results of the growth factor blend.\u00a0<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Chlorella is a green microalgae that stimulates collagen synthesis and also has an anti-collagenase and an anti-elastase effect. Collagenase and elastase are enzymes that break down collagen and elastin, respectively. <\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Since collagen and elastin are responsible for the strength and elasticity of skin, preventing the degradation of these proteins is important for maintaining a youthful complexion.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Saccharide Isomerate is a 100% plant-derived carbohydrate complex that functions as a water-binding agent, thereby improving hydration while also soothing skin.\u00a0<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Hydrolyzed linseed extract rejuvenates the skin by stimulating epidermal cell differentiation, increasing epidermis thickness, and increasing levels of glycosaminoglycans (GAGs) that are naturally found in the connective tissue. Ultimately, hydrolyzed linseed extract helps to improve the skin\u2019s hydration and firmness, resulting in a more youthful complexion.<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">How to Use SkinMedica TNS Advanced Serum?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Dispense SkinMedica TNS Advanced Serum on the back of your hand and blend together before applying to clean skin.<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">Where to Buy SkinMedica TNS Advanced Serum?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">SkinMedica TNS Advanced Serum and other SkinMedica skin care products are sold on the brand\u2019s website (skinmedica.com), as well as through third-party online retailers such as Dermstore.com, Skinstore.com, LovelySkin.com, and others.\u00a0<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">How Much is SkinMedica TNS Advanced Serum?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">SkinMedica TNS Advanced Serum costs $295 USD for just 1 fl oz.<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">What is The\u00a0 SkinMedica Return Policy?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">The SkinMedica return policy states, \u201cWe are committed to offering high-quality, scientifically proven products and want to ensure you are completely satisfied with your order. If you are not satisfied for any reason, we will accept returns within 30 days of your original purchase date.\u201d<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">Is SkinMedica Cruelty-Free?<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">It is unknown if SkinMedica is cruelty-free as there isn\u2019t any information available on the company website, Cruelty Free Kitty, PETA or Leaping Bunny.<\/span><\/p>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">SkinMedica TNS Advanced Serum Reviews<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Unfortunately, this brand does not display SkinMedica reviews on their website, so we went over to LovelySkin.com to get an idea of what customers think of SkinMedica TNS Advanced Serum.<\/span><\/p>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">After more than 700 customer reviews, SkinMedica TNS Advanced Serum has earned an average rating of 4.7 out of 5 stars.\u00a0<\/span><\/p>\n<p dir=\"ltr\">On The Derm Review, there was one negative review: &#8220;<\/p>\n<p>I never really had a chance to try the products to see any results. I\u2019ve purchased this product twice and both times the pump was non functional after 2 or 3 uses. I have read other sites complaining about the non-functioning pump. So quite frankly this product is useless. I am very angry that I wasted my money!<\/p>\n<h2>Our Top Skincare Picks<\/h2>\n\n<table id=\"tablepress-334-no-2\" class=\"tablepress tablepress-id-334 tablepress-responsive\">\n<thead>\n<tr class=\"row-1 odd\">\n\t<th class=\"column-1\"><\/th><th class=\"column-2\">Rank<\/th><th class=\"column-3\">Brand<\/th><th class=\"column-4\"><\/th><th class=\"column-5\"><\/th><th class=\"column-6\"><\/th><th class=\"column-7\"><\/th><th class=\"column-8\">Link<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-hover\">\n<tr class=\"row-2 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  1<\/td><td class=\"column-3\">Carrot &amp; Stick <\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"http:\/\/thedermreview.com\/carrot-and-stick-review\/\" rel=\u201dnofollow\u201d>Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-3 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  2<\/td><td class=\"column-3\">Formulyst<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/formulyst-review\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-4 even\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">  3<\/td><td class=\"column-3\">Skinceuticals<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><a href=\"https:\/\/thedermreview.com\/skinceuticals-reviews\/\">Review<\/a><\/td>\n<\/tr>\n<tr class=\"row-5 odd\">\n\t<td class=\"column-1\"><\/td><td class=\"column-2\">-<\/td><td class=\"column-3\">SkinMedica TNS Advanced Serum<\/td><td class=\"column-4\"><\/td><td class=\"column-5\"><\/td><td class=\"column-6\"><\/td><td class=\"column-7\"><\/td><td class=\"column-8\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-334-no-2 from cache -->\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">Our Verdict<\/span><\/h2>\n<p dir=\"ltr\"><span style=\"font-weight: 400;\">Overall, we think that SkinMedica TNS Advanced Serum is formulated well, although we believe the serum is overpriced for what you get.\u00a0<\/span><\/p>\n<h3 dir=\"ltr\"><span style=\"font-weight: 400; font-size: 18pt;\">Pros<\/span><\/h3>\n<ul>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Formula contains a good blend of innovative ingredients with tried-and-true ingredients like peptides, antioxidants, and botanicals<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Many positive SkinMedica TNS Advanced Serum reviews<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Fragrance-free<\/span><\/li>\n<\/ul>\n<h3 dir=\"ltr\"><span style=\"font-weight: 400; font-size: 18pt;\">Cons<\/span><\/h3>\n<ul>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">High cost ($295 USD for just 1 fl oz)<\/span><\/li>\n<li dir=\"ltr\" style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Unknown if SkinMedica is cruelty-free<\/span><\/li>\n<\/ul>\n<h2 dir=\"ltr\"><span style=\"font-weight: 400;\">What Are Some Alternatives to\u00a0 SkinMedica TNS Advanced Serum?<\/span><\/h2>\n<p dir=\"ltr\"><span>If you\u2019re looking for skincare products to address the signs of aging, we recommend <\/span><strong><a class=\"in-cell-link\" href=\"https:\/\/carrotstick.com\/collections\/best-sellers\/\" rel=\"nofollow noopener\">Carrot &amp; Stick<\/a><\/strong><span>. Carrot &amp; Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin. We recommend <\/span><strong><a href=\"https:\/\/www.carrotstick.com\/product\/the-repair-serum\/\" rel=\"nofollow noopener\">The Repair Serum<\/a><\/strong><strong><a target=\"_blank\" class=\"c-link\" data-stringify-link=\"https:\/\/www.carrotstick.com\/product\/the-defense-serum\/\" delay=\"150\" data-sk=\"tooltip_parent\" href=\"https:\/\/www.carrotstick.com\/product\/the-defense-serum\/\" rel=\"nofollow noopener noreferrer\" data-remove-tab-index=\"true\" tabindex=\"-1\"><\/a><\/strong><span>, followed by <a target=\"_blank\" class=\"c-link\" data-stringify-link=\"https:\/\/www.carrotstick.com\/product\/the-moisturizer\/\" delay=\"150\" data-sk=\"tooltip_parent\" href=\"https:\/\/carrotstick.com\/products\/the-multi-lift-moisturizer\" rel=\"nofollow noopener noreferrer\" data-remove-tab-index=\"true\" tabindex=\"-1\"><strong>The Multi Lift Moisturizer<\/strong><\/a>.<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>TOP SKINCARE PICKS Did you know SkinMedica is the brand that created the first topical growth factors solution back in 2001? Known as the \u201cTNS Recovery Complex\u201d, the launch of this blend of growth factors pioneered the creation of the entire category.\u00a0Then, in 2008, the brand launched their TNS Essential Serum, which remained their most &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;SkinMedica TNA Serum Review&#8221;<\/span><\/a><\/p>\n","protected":false},"author":328,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2238],"tags":[],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>SkinMedica TNA Serum Review - The Dermatology Review<\/title>\n<link rel=\"canonical\" href=\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"SkinMedica TNA Serum Review - The Dermatology Review\" \/>\n<meta property=\"og:description\" content=\"TOP SKINCARE PICKS Did you know SkinMedica is the brand that created the first topical growth factors solution back in 2001? Known as the \u201cTNS Recovery Complex\u201d, the launch of this blend of growth factors pioneered the creation of the entire category.\u00a0Then, in 2008, the brand launched their TNS Essential Serum, which remained their most &hellip; Continue reading &quot;SkinMedica TNA Serum Review&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\" \/>\n<meta property=\"og:site_name\" content=\"The Dermatology Review\" \/>\n<meta property=\"article:published_time\" content=\"2026-01-21T19:00:46+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-03-25T10:15:24+00:00\" \/>\n<meta name=\"author\" content=\"Dr. Kaitlyn Rose\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Dr. Kaitlyn Rose\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\",\"url\":\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\",\"name\":\"SkinMedica TNA Serum Review - The Dermatology Review\",\"isPartOf\":{\"@id\":\"https:\/\/thedermreview.com\/#website\"},\"datePublished\":\"2026-01-21T19:00:46+00:00\",\"dateModified\":\"2026-03-25T10:15:24+00:00\",\"author\":{\"@id\":\"https:\/\/thedermreview.com\/#\/schema\/person\/5b139e0eff87c30b3ffab15f2c526eb4\"},\"breadcrumb\":{\"@id\":\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/thedermreview.com\/skinmedica-tns-advanced-serum-review\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Products\",\"item\":\"https:\/\/thedermreview.com\/category\/products\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"SkinMedica TNA Serum Review\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/thedermreview.com\/#website\",\"url\":\"https:\/\/thedermreview.com\/\",\"name\":\"The Dermatology Review\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/thedermreview.com\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/thedermreview.com\/#\/schema\/person\/5b139e0eff87c30b3ffab15f2c526eb4\",\"name\":\"Dr. Kaitlyn Rose\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/thedermreview.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/855dcab496f96a38a485d064aa5662de?s=96&d=blank&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/855dcab496f96a38a485d064aa5662de?s=96&d=blank&r=g\",\"caption\":\"Dr. Kaitlyn Rose\"},\"description\":\"Dr. Kaitlyn Rose is a licensed pharmacist, certified holistic health coach, freelance writer, and skin care enthusiast. Kaitlyn received her Doctor of Pharmacy degree after graduating with honors from Duquesne University in 2015. Kaitlyn worked in retail pharmacy for about two years after graduation, until she realized the career was not her true passion. Her focus now is on the intersection between science and natural beauty with a focus on wellness and holistic health outcomes. Kaitlyn has a passion for skincare, particularly for learning the science behind why certain ingredients provide amazing benefits and why others are all hype. 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